Scientific publications

MyNewGut ResearchGate page:

 

MyNewGut Project: Microbiome's influence on energy balance and brain development/function put into action to tackle diet-related diseases and behaviour

 

2018

 

Making the gut microbiome more “human” through targeted communication.

Mariani J. & Sadler C.

AgroFOOD Industry Hi Tech, November 2018, Vol 29(6)

 

In press: Gut microbiome is associated with diet, physical activity, and health in children with or without excessive weight gain. 

Rampelli S, Guenther K, Turroni S, Wolters M, Veidebaum T, Yiannis K, …, Ahrens W.

 

Communications Biology. 2018.

 

In press: Cysteine-derived hydrogen sulfide and gut health: a matter of endogenous or bacterial origin.

Blachier F., Beaumont M., & Kim E.

Current Opinion in Clinical Nutrition and Metabolic Care, 2018. Vol 21.

 

In press: Programming Bugs: Microbiota and the Developmental Origins of Brain Health and Disease.

Codagnone, M. G., Spichak, S., O’Mahony, S. M., O’Leary, O. F., Clarke, G., Stanton, C., … Cryan, J. F.

Biological Psychiatry, 2018 June. doi.org/10.1016/j.biopsych.2018.06.014

 

In press: High-protein diets for weight management: Interactions with the intestinal microbiota and consequences for gut health. A position paper by the my new gut study group.

Blachier, F., Beaumont, M., Portune, K. J., Steuer, N., Lan, A., Audebert, M., … Sanz, Y. 

Clinical Nutrition. 2018. doi.org/10.1016/J.CLNU.2018.09.016

 

Interplay Between the Gut-Brain Axis, Obesity and Cognitive Function.

Agustí, A., García-Pardo, M. P., López-Almela, I., Campillo, I., Maes, M., Romaní-Pérez, M., & Sanz, Y.

Frontiers in Neuroscience, 2018 Mar; 12, 155. doi.org/10.3389/fnins.2018.00155

 

Making Sense of … the Microbiome in Psychiatry.

Bastiaanssen, T. F. S., Cowan, C. S. M., Claesson, M. J., Dinan, T. G., & Cryan, J. F.

International Journal of Neuropsychopharmacology. 2018 Aug. doi.org/10.1093/ijnp/pyy067

 

The gut microbiota metabolite indole alleviates liver inflammation in mice.

Beaumont, M., Neyrinck, A. M., Olivares, M., Rodriguez, J., de Rocca Serra, A., Roumain, M., … Delzenne, N. M.

The FASEB Journal, 2018 Jun; fj.201800544. doi.org/10.1096/fj.201800544

  

Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.

Catry, E., Bindels, L. B., Tailleux, A., Lestavel, S., Neyrinck, A. M., Goossens, J.-F., … Delzenne, N. M.

Gut, 2018; 67(2), 271–283. doi.org/10.1136/gutjnl-2016-313316

 

LC-MS/MS Analysis of Bile Acids.

Krautbauer, S., & Liebisch, G.

In Methods in molecular biology, 2018; 1730, 103–110. doi.org/10.1007/978-1-4939-7592-1_8

 

Implication of trans-11,trans-13 conjugated linoleic acid in the development of hepatic steatosis.

Pachikian, B. D., Druart, C., Catry, E., Bindels, L. B., Neyrinck, A. M., Larondelle, Y., … Delzenne, N. M.

PLOS ONE, 2018 Feb; 13(2), e0192447. doi.org/10.1371/journal.pone.0192447

  

Short-chain fatty acids: microbial metabolites that alleviate stress-induced brain-gut axis alterations.

van de Wouw, M., Boehme, M., Lyte, J. M., Wiley, N., Strain, C., O’Sullivan, O., … Cryan, J. F.

The Journal of Physiology, 2018 July; 596(20), 4923–4944. doi.org/10.1113/JP276431

 

Metformin.

Rodriguez, J., Hiel, S., & Delzenne, N. M.

Current Opinion in Clinical Nutrition and Metabolic Care, 2018 Jul; 21(4), 294–301. doi.org/10.1097/MCO.0000000000000468

 

The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice.

Kindt, A., Liebisch, G., Clavel, T., Haller, D., Hörmannsperger, G., Yoon, H., … Ecker, J.  

Nature Communications. September 2018; 9. doi: 10.1038/s41467-018-05767-4.

 

The Potential Role of the Dipeptidyl Peptidase-4-Like Activity From the Gut Microbiota on the Host Health.

Olivares M, Schüppel V, Hassan AM, Beaumont M, Neyrinck AM, Bindels LB, Benítez-Páez A, Sanz Y, Haller D, Holzer P and Delzenne NM

Front. Microbiol. 22 August 2018. Open Access doi: 10.3389/fmicb.2018.01900

 

Towards microbiome-informed dietary recommendations for promoting metabolic and mental health: Opinion papers of the MyNewGut project
Sanz, Y., Romaní-Perez, M., Benítez-Páez, A., Portune, K. J., Brigidi, P., Rampelli, S., … Kamp, J.-W. van der.

Clinical Nutrition. 2018 July;1-7. Open Access Article in Press doi:  10.1016/j.clnu.2018.07.007.  

 

A Validated, Fast Method for Quantification of Sterols and Gut Microbiome Derived 5α/β-Stanols in Human Feces by Isotope Dilution LC–High-Resolution MS.

Schött, H.-F., Krautbauer, S., Höring, M., Liebisch, G., & Matysik, S. 

Analytical Chemistry. 2018 June; 90(14), 8487–8494. 

 

High-fat diet induces depression-like behaviour in mice associated with changes in microbiome, neuropeptide Y, and brain metabolome
Hassan AM, Mancano G, Kashofer K, Fröhlich EE, Matak A, Mayerhofer R, Reichmann F, Olivares M, Neyrinck AM, Delzenne NM, Claus SP, Holzer P.
Nutritional Neuroscience. 2018 April;1-17. doi: 10.1080/1028415X.2018.1465713. 

The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice
Olivares M, Neyrinck AM, Pötgens SA, Beaumont M, Salazar N, Cani PD, Bindels LB, Delzenne NM.
Diabetologia. 2018 May;1-11. doi: 10.1007/s00125-018-4647-6. 

 

2017

 

Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration.

Dinan, T. G., & Cryan, J. F.

The Journal of Physiology, 2017 Jan; 595(2), 489–503. doi.org/10.1113/JP273106

 

Evolution of gut microbiota composition from birth to 24 weeks in the INFANTMET Cohort.

Hill, C. J., Lynch, D. B., Murphy, K., Ulaszewska, M., Jeffery, I. B., O’Shea, C. A., … Stanton, C.

Microbiome, 2017 Jan; 5(1), 4. doi.org/10.1186/s40168-016-0213-y

 

Bifidobacterium pseudocatenulatum CECT 7765 Ameliorates Neuroendocrine Alterations Associated with an Exaggerated Stress Response and Anhedonia in Obese Mice.
Agusti A, Moya-Pérez A, Campillo I, Montserrat-de la Paz S, Cerrudo V, Perez-Villalba A, Sanz Y.
Mol Neurobiol. 2017 Sep;54:in press. doi: 10.1007/s12035-017-0768-z.
PMID: 28921462

 

 

Quantity and source of dietary protein influence metabolite production by gut microbiota and rectal mucosa gene expression: a randomized, parallel, double-blind trial in overweight humans.

Beaumont M, Portune KJ, Steuer N, Lan A, Cerrudo V, Audebert M, Dumont F, Mancano G, Khodorova N, Andriamihaja M, Airinei G, Tomé D, Benamouzig R, Davila AM, Claus SP, Sanz Y, Blachier F.
Am J Clin Nutr. 2017 Oct;106(4):1005-1019. doi: 10.3945/ajcn.117.158816.
PMID: 28903954

Innovation in microbiome-based strategies for promoting metabolic health.
Romaní-Pérez M, Agusti A, Sanz Y.
Curr Opin Clin Nutr Metab Care. 2017 Nov;20(6):484-491. doi: 10.1097/MCO.0000000000000419.
PMID: 28862999

The Glycolytic Versatility of Bacteroides uniformis CECT 7771 and Its Genome Response to Oligo and Polysaccharides.
Benítez-Páez A, Gómez Del Pulgar EM, Sanz Y.
Front Cell Infect Microbiol. 2017 Aug 25;7:383. doi: 10.3389/fcimb.2017.00383.
PMID: 28971068

Multi-locus and long amplicon sequencing approach to study microbial diversity at species level using the MinIONTM portable nanopore sequencer.
Benítez-Páez A, Sanz Y.
Gigascience. 2017 Jul;6(7):1-12. doi: 10.1093/gigascience/gix043.
PMID: 28605506

Bifidobacterium CECT 7765 modulates early stress-induced immune, neuroendocrine and behavioral alterations in mice.
Moya-Pérez A, Perez-Villalba A, Benítez-Páez A, Campillo I, Sanz Y.
Brain Behav Immun. 2017 Oct;65:43-56. doi: 10.1016/j.bbi.2017.05.011.
PMID: 28512033

 

Lost in translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects. 
Kelly, J. R., Allen, A. P., Temko, A., Hutch, W., Kennedy, P. J., Farid, N., ... & Clarke, G.

Brain Behav Immun. 2017 Mar; 61:50-59. doi: 10.1016/j.bbi.2016.11.018

 

 Changes in the luminal environment of the colonic epithelial cells and physiopathological consequences.
Blachier F, Beaumont M, Andriamihaja M, Davila AM, Lan A, Grauso M, Armand L, Benamouzig R, Tomé D.
Am J Pathol. 2017 Mar; 187(3):476-486. doi: 10.1016/j.ajpath.2016.11.015.
PMID: 28082121

Gut microbiota, diet and obesity-related disorders - the good, the bad and the future challenges.
Portune KJ, Benítez-Páez A, Del Pulgar EM, Cerrudo V, Sanz Y.
Mol Nutr Food Res. 2017 Jan;61(1):1600252. doi: 10.1002/mnfr.201600252.
PMID: 27287778

 2016

 

MyNewGut Special Issue: Unravelling the role of the gut microbiome in energy balance and brain development and function: the European project MyNewGut

Brigidi P, Sanz Y.
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.11.002.

 

Impact of dietary fiber and fat on gut microbiota re-modeling and metabolic health.
Benítez-Páez A, Gómez Del Pulgar EM, Kjølbæk L, Kirchner Brahe L, Astrup A, Hingstrup Larsen L, Sanz Y.
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.11.001.

 

Gut microbiota role in dietary protein metabolism and health-related outcomes: The two sides of the coin.
Portune K.J, Beaumont M, Davila A, Tomé D, Blachier F, Sanz Y.
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.08.011.

 

Interplay between gut microbiota, its metabolites and human metabolism: Dissecting cause from consequence.
Hartstra A.V, Nieuwdorp M, Herrema H. 
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.08.009.

 

Metabolomics of fecal samples: A practical consideration.
Matysik S, Le Roy C, Gerhard L, Claus S.
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.05.011.

Microbiome and metabolic disorders related to obesity: Which lessons to learn from experimental models?
Neyrinck AM, Schüppel VL, Lockett T, Haller D, Delzenne NM. 

Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.08.012.

 

Microbiota and lifestyle interactions through the lifespan.
Rampelli S, Candela M, Turroni S, Biagi E, Pflueger M, Wolters M, Ahrens W, Brigidi P.
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.03.003.

 

Role of microbiota during early life on child's neurodevelopment.
Cerdóa T, García-Valdésa L, Altmäeb S, Ruízd A, Suárezd A, Campoy C. 
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.08.007.

 

Microbiome in brain function and mental health.
Kennedy PJ, Murphy A.B, Cryan JF, Ross PR, Dinan TG. 
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.05.001.

 

The human gut microbiome, diet, and health: “Post hoc non ergo propter hoc”.
Roeselers G, Bouwman J, Levin E.
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.08.010.

 

Insulin resistance as key factor for linking modulation of gut microbiome to health claims and dietary recommendations to tackle obesity.          

Loman S, Van der Kamp JW.

Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.10.008.

 

Communication and impact through targeted channels and media.

Giordani A, Sadler C,Fernández L.

Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.10.007.

 

The role of microbiota and Intestinal permeability in the pathophysiology of autoimmune and neuroimmune processes with an emphasis on Inflammatory Bowel Disease, Type 1, Diabetes and Chronic Fatigue Syndrome. Morris G, Berk M, Carvalho AF, Caso JR, Sanz Y, Maes M.

Curr Pharm Des. 2016 Sep 14. [Epub ahead of print]

 

Intestinal dysbiosis, gut hyperpermeability and bacterial translocation: missing links between depression, obesity and type 2 diabetes?  Slyepchenko A, Maes M, Machado-Veira R, Anderson G, Solmi M, Sanz Y, Berk M, Köhler CA, Carvalho AF.

Curr Pharm Des. 2016 Sep 22. [Epub ahead of print]

 

The Role of the Microbial Metabolites Including Tryptophan Catabolites and Short Chain Fatty Acids in the Pathophysiology of Immune-Inflammatory and Neuroimmune Disease.
Morris G, Berk M, Carvalho A, Caso JR, Sanz Y, Walder K, Maes M.
Molecular Neurobiology. 2016 Jun 27. doi: 10.1007/s12035-016-0004-2.
PMID: 27349436.

 

The gut microbiota: a major player in the toxicity of environmental pollutants? 

Claus S, Guillou H, Ellero-Simatos S.

Biofilms and Microbiomes. 2016 May 4. doi: 10.1038/npjbiofilms.2016.3

 

Genome structure of the symbiont Bifidobacterium pseudocatenulatum CECT 7765 and gene expression profiling in response to lactulose-derived oligosaccharides.
Benítez-Páez A, Moreno FJ, Sanz ML, Sanz Y. 
Front Microbiol. 2016 Apr 29;7:624. doi: 10.3389/fmicb.2016.00624.
PMID: 27199952.

ViromeScan: a new tool for metagenomic viral community profiling.
Rampelli S, Soverini M, Turroni S, Quercia S, Biagi E, Brigidi P, Candela M.
BMC Genomics. 2016 March 1. doi: 10.1186/s12864-016-2446-3.
PMID: 26932765

 

Detrimental effects for colonocytes of an increased exposure to luminal hydrogen sulfide: The adaptive response.
Beaumont M, Andriamihaja M, Lan A, Khodorova N, Audebert M, Blouin JM, Grauso M, Lancha L, Benetti PH, Benamouzig R, Tome D, Bouillaud F, Davila AM, Blachier F.
Free Radic Biol Med. 2016 April. doi: 10.1016/j.freeradbiomed.2016.01.028.
PMID: 26849947

Species-level resolution of 16S rRNA gene amplicons sequenced through the MinION™ portable nanopore sequencer.
Benítez-Páez A, Portune KJ, Sanz Y. 
Gigascience. 2016 Jan 28;5:4. doi: 10.1186/s13742-016-0111-z.
PMID: 26823973.

Safety Assessment of Bacteroides uniformis CECT 7771 Isolated from Stools of Healthy Breast-Fed Infants.
Fernández-Murga ML, Sanz Y.
PLoS One. 2016 Jan 19;11(1):e0145503. doi: 10.1371/journal.pone.0145503. 
PMID: 26784747

Bifidobacterium pseudocatenulatum CECT7765 induces an M2 anti-inflammatory transition in macrophages from patients with cirrhosis.
Moratalla A, Caparrós E, Juanola O, Portune K, Puig-Kröger A, Estrada L,Bellot P, Gómez-Hurtado I, Piñero P, Zapater P, González-Navajas JM, Such J, Sanz Y, Francés R.
Journal of Hepatology. 2016 Jan. doi: 10.1016/j.jhep.2015.08.020.
PMID: 26334579.  

 

2015

 

Birth by Caesarean Section and the Risk of Adult Psychosis: A Population Based Cohort Study.
O'Neill SM, Curran EA, Dalman C, Kenny LC, Kearney PM, Clarke G, Cryan JF, Dinan TG, Khashan AS.
Schizophr Bull. 2015 Nov; 45 (3): 633-641. doi: 10.1093/schbul/sbv152.
PMID: 26615187.

Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders.
Kelly JR, Kennedy PJ, Cryan JF, Dinan TG, Clarke G, Hyland NP. 
Front Cell Neurosci. 2015 Oct; 9: 392. doi: 10.3389/fncell.2015.00392.
PMID: 26528128.  

 

Adult Hippocampal Neurogenesis Is Regulated by the Microbiome.
Ogbonnaya ES, Clarke G, Shanahan F, Dinan TG, Cryan JF, O'Leary OF.
Biological Psychiatry. 2015 Aug; 78(4). doi: 10.1016/j.biopsych.2014.12.023.
PMID: 25700599.

When ageing meets the blues: Are current antidepressants effective in depressed aged patients?
Felice D, O'Leary OF, Cryan JF, Dinan TG, Gardier AM, Sanchez C, David DJ.
Neuroscience and Behavioural Reviews. Aug 2015; 55:478-497. doi: 10.1016/j.neubiorev.2015.06.005.

PMID: 26054791.

 

Foodomics for personalized nutrition: how far are we?
Vimaleswaran KS, Le Roy CI, Claus SP.
Current Opinion in Food Science. 2015 Aug; 4:129-135. doi: 10.1016/j.cofs.2015.07.001.

The deleterious metabolic and genotoxic effects of the bacterial metabolite p-cresol on colonic epithelial cells.

Andriamihaja M, Lan A, Beaumont M, Audebert M, Wong X, Yamada K, Yin Y, Tomé D, Carrasco-Pozo C, Gotteland M, Kong X, Blachier F.
Free Radic Biol Med. 2015 Aug; 85:219-27. doi: 10.1016/j.freeradbiomed.2015.04.004. 
PMID: 25881551

 

Gut microorganisms as promising targets for the management of type 2 diabetes.
Delzenne NM, Cani PD, Everhard A, Neyrinck AM, Bindels LB.
Diabetologia. 2015 July; 58 (10): 2206-2217.
PMID: 26224102

 

Microbiota and host determinants of behavioural phenotype in maternally separated mice.
De Palma G, Blennerhassett P, Lu J, Deng Y, Park AJ, Green W, Denou E, Silva MA, Santacruz A, Sanz Y, Surette MG, Verdu EF, Collins SM, Bercik P.
Nature Communications. 2015 July 28; 6: 7735. doi: 10.1038/ncomms8735.
PMID: 26218677

Understanding the role of gut microbiome in metabolic disease risk.
Sanz Y, Olivares M, Moya-Pérez Á, Agostoni C.
Pediatr Res. 2015 Jan; 77(1-2):236-44. doi: 10.1038/pr.2014.170. Epub 2014 Oct 14.
PMID: 25314581.

 

Insights into the role of the microbiome in obesity and type 2 diabetes.
Hartstra AV, Bouter KE, Bäckhed F, Nieuwdorp M.
Diabetes Care. 2015 Jan; 38(1):159-65. doi: 10.2337/dc14-0769.
PMID: 25538312.

 

2014

 

Mammalian-microbial cometabolism of L-carnitine in the context of atherosclerosis.
Claus SP.
Cell Metab. 2014 Nov 4; 20(5):699-700. doi: 10.1016/j.cmet.2014.10.014. 
Epub 2014 Nov 4.
PMID: 25440049.

 

Development of personalized functional foods needs metabolic profiling.
Claus SP.
Curr Opin Clin Nutr Metab Care. 2014 Nov; 17(6):567-73. doi: 10.1097/MCO.0000000000000107.
PMID: 25137506.

 

High protein diet modifies colonic microbiota and luminal environment but not colonocyte metabolism in the rat model: The increased luminal bulk connection.
Liu X, Blouin JM, Santacruz A, Lan A, Andriamihaja M, Wilkanowicz S, Benetti PH, Tome D, Sanz Y, Blachier F, Davilla AM. 
American Journal of Physiology. 2014 June 26. doi: 10.1152/ajpgi.00400.2013
PMID: 24970777.