Scientific publications

MyNewGut ResearchGate page:


MyNewGut Project: Microbiome's influence on energy balance and brain development/function put into action to tackle diet-related diseases and behaviour



Holdemanella biformis improves glucose tolerance and regulates GLP-1 signaling in obese mice.

Romaní-Pérez M, López-Almela I, Bullich-Vilarrubias C, Rueda-Ruzafa L, Gómez Del Pulgar EM, Benítez-Páez A, Liebisch G, Lamas JA, Sanz Y.
FASEB J, 2021. Vol 35:e21734.

Bacteroides uniformis CECT 7771 alleviates inflammation within the gut-adipose tissue axis involving TLR5 signaling in obese mice.

Fabersani E, Portune K, Campillo I, López-Almela I, la Paz SM, Romaní-Pérez M, Benítez-Páez A, Sanz Y.
Sci Rep, 2021. Vol 11:11788.

Sex, Food, and the Gut Microbiota: Disparate Response to Caloric Restriction Diet with Fiber Supplementation in Women and Men.

Benítez-Páez A, Hess AL, Krautbauer S, Liebisch G, Christensen L, Hjorth MF, Larsen TM, Sanz Y.
Mol Nutr Food Res, 21. Vol 65:e2000996.

Complete Genome Sequence of Phascolarctobacterium faecium G 104, Isolated from the Stools of a Healthy Lean Donor.

Rachek S, Nikpoor N, Gómez Del Pulgar EM, Gonzaga A, Sanz Y, Tompkins TA.
Microbiol Resour Announc, 2021. Vol 10:e01054-20.

Bacteroides uniformis combined with fiber amplifies metabolic and immune benefits in obese mice.

López-Almela I, Romaní-Pérez M, Bullich-Vilarrubias C, Benítez-Páez A, Gómez Del Pulgar EM, Francés R, Liebisch G, Sanz Y.
Gut Microbes, 2021. Vol 13:1-20.


Strand-wise and bait-assisted assembly of nearly-full rrn operons applied to assess species engraftment after faecal microbiota transplantation.

Benítez-Páez A, Hartstra AV, Nieuwdorp M, Sanz Y.
bioRxiv, 2020. Vol 2020:292896.

Infusion of donor feces affects the gut-brain axis in humans with metabolic syndrome.

Hartstra AV, Schüppel V, Imangaliyev S, Schrantee A, Prodan A, Collard D, Levin E, Dallinga-Thie G, Ackermans MT, Winkelmeijer M, Havik SR, Metwaly A, Lagkouvardos I, Nier A, Bergheim I, Heikenwalder M, Dunkel A, Nederveen AJ, Liebisch G, Mancano G, Claus SP, Benítez-Páez A, la Fleur SE, Bergman JJ, Gerdes V, Sanz Y, Booij J, Kemper E, Groen AK, Serlie MJ, Haller D, Nieuwdorp M.
Mol Metab, 2020. Vol 42:101076.

Anhedonia induced by high-fat diet in mice depends on gut microbiota and leptin.

Hassan AM, Mancano G, Kashofer K, Liebisch G, Farzi A, Zenz G, Claus SP, Holzer P.
Nutr Neurosci, 2020. Vol 23:1-14.

Depletion of Blautia species in the microbiota of obese children relates to intestinal inflammation and metabolic phenotype worsening.

Benítez-Páez A, Gómez del Pulgar EM, López-Almela I, Moya-Pérez A, Codoñer-Franch P, Sanz Y.
mSystems, 2020. Vol 5:e00857-19.

Levels of circulating miR-122 are associated with weight loss and metabolic syndrome.

Hess AL, Larsen LH, Udesen PB, Sanz Y, Larsen TM, Dalgaard LT.
Obesity (Silver Spring), 2020. Vol 28:493-501.

Safety assessment of Bacteroides uniformis CECT 7771, a symbiont of the gut microbiota in infants.

Gómez Del Pulgar EM, Benítez-Páez A, Sanz Y.
Nutrients, 2020. Vol 12, pii: E551.



The Janus Face of Cereals: Wheat-Derived Prebiotics Counteract the Detrimental Effect of Gluten on Metabolic Homeostasis in Mice Fed a High-Fat/High-Sucrose Diet.

Marta Olivares, Julie Rodriguez, Sarah A Pötgens, Audrey M Neyrinck, Patrice D Cani, Laure B Bindels , Nathalie M Delzenne

Mol Nutr Food Res, 2019. Vol 63:e1900632. doi: 10.1002/mnfr.201900632.


Contribution of the gut microbiota to the regulation of host metabolism and energy balance: a focus on the gut-liver axis.

Delzenne NM, Knudsen C, Beaumont M, Rodriguez J, Neyrinck AM, Bindels LB.

Proc Nutr Soc, 2019. Vol 78:319-328. doi: 10.1017/S0029665118002756


The effect of inulin and resistant maltodextrin on weight loss during energy restriction: a randomised, placebo-controlled, double-blinded intervention.

Hess AL, Benítez-Páez A, Blædel T, Larsen LH, Iglesias JR, Madera C, Sanz Y, Larsen TM.
Eur J Nutr, 2019. Vol 59:in press.

Multi-omics approach to unravelling the microbiome-mediated effects of arabinoxylan-oligosaccharides in overweight humans.

Benítez-Páez A, Kjølbæk L, Gómez del Pulgar EM, Brahe LK, Astrup A, Matysik S, Schött HF, Krautbauer S, Liebisch G, Boberska J, Claus P, Rampelli S, Brigidi P, Larsen LH, Sanz Y.
mSystems, 2019. Vol 4:e00209-19.

Nutritional interest of dietary fiber and prebiotics in obesity: Lessons from the MyNewGut consortium.

Delzenne NM, Olivares M, Neyrinck AM, Beaumont M, Kjølbæk L, Larsen TM, Benítez-Páez A, Romaní-Pérez M, Garcia-Campayo V, Bosscher D, Sanz Y, van der Kamp JW.
Clinical Nutrition, 2019. Vol 38.

Arabinoxylan oligosaccharides and polyunsaturated fatty acid effects on gut microbiota and metabolic markers in overweight individuals with signs of metabolic syndrome: a randomized cross-over trial.

Kjølbæk L, Benítez-Páez A, Gómez Del Pulgar EM, Brahe LK, Liebisch G, Matysik S, Rampelli S, Vermeiren J, Brigidi P, Larsen LH, Astrup A, Sanz Y.
Clinical Nutrition, 2019. Vol 38.

Programming Bugs: Microbiota and the Developmental Origins of Brain Health and Disease.

Codagnone, M. G., Spichak, S., O’Mahony, S. M., O’Leary, O. F., Clarke, G., Stanton, C., … Cryan, J. F.
Biological Psychiatry, 2019. Vol 85.

Cysteine-derived hydrogen sulfide and gut health: a matter of endogenous or bacterial origin.

Blachier F., Beaumont M., & Kim E.
Current Opinion in Clinical Nutrition and Metabolic Care, 2019. Vol 21. doi: 10.1097/MCO.0000000000000526

Dietary fat, the gut microbiota, and metabolic health – a systematic review conducted within the MyNewGut project.

Wolters M., Ahrens, J., Romani Parez, M., Watkins, C., Sanz, Y., Benítez-Páez, A., Stanton, C., Günther, K. 
Clinical Nutrition, 2019. doi: 10.1016/j.clnu.2018.12.024


Feeding melancholic microbes: MyNewGut recommendations on diet and mood.

Dinan TG, Stanton C, Long-Smith C, Kennedy P, Cryan JF, Cowan CSM, Cenit MC, van der Kamp JW, Sanz Y.
Clinical Nutrition, 2019.


The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice.

Kindt A, Liebisch G, Clavel T, Haller D, Hörmannsperger G, Yoon H, Kolmeder D, Sigruener A, Krautbauer S, Seeliger C, Ganzha A, Schweizer S, Morisset R, Strowig T, Daniel H, Helm D, Küster B, Krumsiek J, Ecker J. Nature Communications, 2018. Vol 9:3760.

Gut microbial functional maturation and succession during human early life.

Cerdó, T., Ruiz, A., Acuña, I., Jáuregui, R., Jehmlich, N., Haange, S.-B., von Bergen, M., Suárez, A., Campoy, C.
Environmental Microbiology, 2018. Vol 20.


Maternal obesity is associated with gut microbial metabolic potential in offspring during infancy.

Cerdó, T., Ruiz, A., Torres-Espínola, F.J., García-Valdés, L., Teresa Segura, M., Suárez, A., Campoy, C.
Journal of Physiology and Biochemistry, 2018. Vol. 74. Doi: 10.1007/s13105-017-0577-x


Particle size determines the anti-inflammatory effect of wheat bran in amodel of fructose over-consumption: Implication of the gut microbiota.
Suriano, S., Neyrinck, A.N., Verspreet, J., Olivares, M., Leclercq, S., de Wiele, T.V., Courtin, C.M., Cani, P.D., Bindels, L.B., Delzenne, N.M.
Journal of Functional Foods, 2018. Vol. 41.

LC-MS/MS Analysis of Bile Acids.
Krautbauer, S., Liebisch, G.
Methods in Molecular Biology, 2018. Vol. 1730. DOI: 10.1007/978-1-4939-7592-1_8.

Identification of gut microbiota components potentially beneficial for obesity.
Gómez Del Pulgar Villanueva, E. M.; Supervisors: Benítez-Páez, A. and Sanz, Y.
2014-2018. Dissertation

Finding the needle in the haystack: systematic identification of psychobiotics.
Bambury, A., Sandhu, K., Cryan, J.F, Dinan, T.G.
British Journal of Pharmacology, 2018. 175(24). DOI: 10.1111/bph.14127

Structure and function of Intestinal Gut Microbiota in infants born to obese mothers and its effect on neurodevelopment during the first months of life.
Cerdó, T.,Suárez, A., Campoy, C.
University of Granada, 2018. Dissertation.


Improved hemodynamic and liver function in portal hypertensive cirrhotic rats after administration of B. pseudocatenulatum CECT 7765.
Gómez-Hurtado, I., Zapater, P., Portune, K., Juanola, O., Fernández-Iglesias, A., González-Navajas, J.M., Gracia-Sancho, J., Sanz, Y., Francés, R.
European Journal of Nutrition, 2018. Doi: 10.1007/s00394-018-1709-y


Making the gut microbiome more “human” through targeted communication.

Mariani J. & Sadler C.

AgroFOOD Industry Hi Tech, November 2018, Vol 29(6)


Pre-obese children’s dysbiotic gut microbiome and unhealthy diets may predict the development of obesity.

Rampelli S, Guenther K, Turroni S, Wolters M, Veidebaum T, Yiannis K, …Ahrens W.

Communications Biology. 2018. doi: 10.1038/s42003-018-0221-5.


In press: High-protein diets for weight management: Interactions with the intestinal microbiota and consequences for gut health. A position paper by the my new gut study group.

Blachier, F., Beaumont, M., Portune, K. J., Steuer, N., Lan, A., Audebert, M., … Sanz, Y. 

Clinical Nutrition. 2018.


Interplay Between the Gut-Brain Axis, Obesity and Cognitive Function.

Agustí, A., García-Pardo, M. P., López-Almela, I., Campillo, I., Maes, M., Romaní-Pérez, M., & Sanz, Y.

Frontiers in Neuroscience, 2018 Mar; 12, 155.


Making Sense of … the Microbiome in Psychiatry.

Bastiaanssen, T. F. S., Cowan, C. S. M., Claesson, M. J., Dinan, T. G., & Cryan, J. F.

International Journal of Neuropsychopharmacology. 2018 Aug.


The gut microbiota metabolite indole alleviates liver inflammation in mice.

Beaumont, M., Neyrinck, A. M., Olivares, M., Rodriguez, J., de Rocca Serra, A., Roumain, M., … Delzenne, N. M.

The FASEB Journal, 2018 Jun; fj.201800544.


Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.

Catry, E., Bindels, L. B., Tailleux, A., Lestavel, S., Neyrinck, A. M., Goossens, J.-F., … Delzenne, N. M.

Gut, 2018; 67(2), 271–283.


LC-MS/MS Analysis of Bile Acids.

Krautbauer, S., & Liebisch, G.

In Methods in molecular biology, 2018; 1730, 103–110.


Implication of trans-11,trans-13 conjugated linoleic acid in the development of hepatic steatosis.

Pachikian, B. D., Druart, C., Catry, E., Bindels, L. B., Neyrinck, A. M., Larondelle, Y., … Delzenne, N. M.

PLOS ONE, 2018 Feb; 13(2), e0192447.


Short-chain fatty acids: microbial metabolites that alleviate stress-induced brain-gut axis alterations.

van de Wouw, M., Boehme, M., Lyte, J. M., Wiley, N., Strain, C., O’Sullivan, O., … Cryan, J. F.

The Journal of Physiology, 2018 July; 596(20), 4923–4944.



Rodriguez, J., Hiel, S., & Delzenne, N. M.

Current Opinion in Clinical Nutrition and Metabolic Care, 2018 Jul; 21(4), 294–301.


The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice.

Kindt, A., Liebisch, G., Clavel, T., Haller, D., Hörmannsperger, G., Yoon, H., … Ecker, J.  

Nature Communications. September 2018; 9. doi: 10.1038/s41467-018-05767-4.


The Potential Role of the Dipeptidyl Peptidase-4-Like Activity From the Gut Microbiota on the Host Health.

Olivares M, Schüppel V, Hassan AM, Beaumont M, Neyrinck AM, Bindels LB, Benítez-Páez A, Sanz Y, Haller D, Holzer P and Delzenne NM

Front. Microbiol. 22 August 2018. Open Access doi: 10.3389/fmicb.2018.01900


Towards microbiome-informed dietary recommendations for promoting metabolic and mental health: Opinion papers of the MyNewGut project
Sanz, Y., Romaní-Perez, M., Benítez-Páez, A., Portune, K. J., Brigidi, P., Rampelli, S., … Kamp, J.-W. van der.

Clinical Nutrition. 2018 July;1-7. Open Access Article in Press doi:  10.1016/j.clnu.2018.07.007.  


A Validated, Fast Method for Quantification of Sterols and Gut Microbiome Derived 5α/β-Stanols in Human Feces by Isotope Dilution LC–High-Resolution MS.

Schött, H.-F., Krautbauer, S., Höring, M., Liebisch, G., & Matysik, S. 

Analytical Chemistry. 2018 June; 90(14), 8487–8494. 


High-fat diet induces depression-like behaviour in mice associated with changes in microbiome, neuropeptide Y, and brain metabolome
Hassan AM, Mancano G, Kashofer K, Fröhlich EE, Matak A, Mayerhofer R, Reichmann F, Olivares M, Neyrinck AM, Delzenne NM, Claus SP, Holzer P.
Nutritional Neuroscience. 2018 April;1-17. doi: 10.1080/1028415X.2018.1465713. 

The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice
Olivares M, Neyrinck AM, Pötgens SA, Beaumont M, Salazar N, Cani PD, Bindels LB, Delzenne NM.
Diabetologia. 2018 May;1-11. doi: 10.1007/s00125-018-4647-6. 




Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration.

Dinan, T. G., & Cryan, J. F.

The Journal of Physiology, 2017 Jan; 595(2), 489–503.


Evolution of gut microbiota composition from birth to 24 weeks in the INFANTMET Cohort.

Hill, C. J., Lynch, D. B., Murphy, K., Ulaszewska, M., Jeffery, I. B., O’Shea, C. A., … Stanton, C.

Microbiome, 2017 Jan; 5(1), 4.


Bifidobacterium pseudocatenulatum CECT 7765 Ameliorates Neuroendocrine Alterations Associated with an Exaggerated Stress Response and Anhedonia in Obese Mice.
Agusti A, Moya-Pérez A, Campillo I, Montserrat-de la Paz S, Cerrudo V, Perez-Villalba A, Sanz Y.
Mol Neurobiol. 2017 Sep;54:in press. doi: 10.1007/s12035-017-0768-z.
PMID: 28921462


Quantity and source of dietary protein influence metabolite production by gut microbiota and rectal mucosa gene expression: a randomized, parallel, double-blind trial in overweight humans.

Beaumont M, Portune KJ, Steuer N, Lan A, Cerrudo V, Audebert M, Dumont F, Mancano G, Khodorova N, Andriamihaja M, Airinei G, Tomé D, Benamouzig R, Davila AM, Claus SP, Sanz Y, Blachier F.
Am J Clin Nutr. 2017 Oct;106(4):1005-1019. doi: 10.3945/ajcn.117.158816.
PMID: 28903954


Innovation in microbiome-based strategies for promoting metabolic health.
Romaní-Pérez M, Agusti A, Sanz Y.
Curr Opin Clin Nutr Metab Care. 2017 Nov;20(6):484-491. doi: 10.1097/MCO.0000000000000419.
PMID: 28862999

The Glycolytic Versatility of Bacteroides uniformis CECT 7771 and Its Genome Response to Oligo and Polysaccharides.

Benítez-Páez A, Gómez Del Pulgar EM, Sanz Y.
Front Cell Infect Microbiol. 2017 Aug 25;7:383. doi: 10.3389/fcimb.2017.00383.
PMID: 28971068

Multi-locus and long amplicon sequencing approach to study microbial diversity at species level using the MinIONTM portable nanopore sequencer.
Benítez-Páez A, Sanz Y.
Gigascience. 2017 Jul;6(7):1-12. doi: 10.1093/gigascience/gix043.
PMID: 28605506

Bifidobacterium CECT 7765 modulates early stress-induced immune, neuroendocrine and behavioral alterations in mice.

Moya-Pérez A, Perez-Villalba A, Benítez-Páez A, Campillo I, Sanz Y.
Brain Behav Immun. 2017 Oct;65:43-56. doi: 10.1016/j.bbi.2017.05.011.
PMID: 28512033


Lost in translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects. 
Kelly, J. R., Allen, A. P., Temko, A., Hutch, W., Kennedy, P. J., Farid, N., ... & Clarke, G.

Brain Behav Immun. 2017 Mar; 61:50-59. doi: 10.1016/j.bbi.2016.11.018


Changes in the luminal environment of the colonic epithelial cells and physiopathological consequences.
Blachier F, Beaumont M, Andriamihaja M, Davila AM, Lan A, Grauso M, Armand L, Benamouzig R, Tomé D.
Am J Pathol. 2017 Mar; 187(3):476-486. doi: 10.1016/j.ajpath.2016.11.015.
PMID: 28082121

Gut microbiota, diet and obesity-related disorders - the good, the bad and the future challenges.

Portune KJ, Benítez-Páez A, Del Pulgar EM, Cerrudo V, Sanz Y.
Mol Nutr Food Res. 2017 Jan;61(1):1600252. doi: 10.1002/mnfr.201600252.
PMID: 27287778

Behavioural and neurochemical consequences of chronic gut microbiota depletion during adulthood in the rat.

A.E. Hoban, R.D. Moloney, A.V. Golubeva, K.A. McVey Neufeld, O. O'Sullivan, E. Patterson, C. Stanton, T.G. Dinan, G. Clarke, J.F. Cryan.
Neuroscience, 2017. Vol. 344.

The Trier Social Stress Test: Principles and practice.
Allen, A.P., Kennedy, P.J., Dockray, S., Cryan, J.F., Dinan, T.G., Clarke, G.
Neurobiology of Stress, 2017. Vol. 6.

Microbial therapeutics designed for infant health.
Watkins, C., Stanton, C., Ryan, C. A., Ross, R. P.
Frontiers of Nutrition, 2017.

The microbiota-gut-brain axis in obesity.
Torres-Fuentes, C., Schellekens, H., Dinan, T.G., Cryan, J.F.
Gastroenterology & Hepatology, 2017. 2(10).

Brain-Gut-Microbiota Axis and Mental Health.
Dinan, T.G., Cryan, J.F.
Psychosomatic Medicine, 2017. 79(8). Doi: 10.1097/PSY.0000000000000519

Revisiting Metchnikoff: Age-related alterations in microbiota-gut-brain axis in the mouse.
Scott, K.A., Ida, M., Peterson, V.L., Prenderville, J.A., Moloney, G.M., Izumo, T., Murphy, K., Murphy, A., Ross, R.P., Stanton, C., Dinan, T.G., Cryan, J.F.
Brain, Behavior, and Immunity, 2017. Vol. 65.

Choline theft - an inside job.
Mora-Oritz, M., Claus, S.P.
Cell Host & Microbe, 2017. 22(3).

How do probiotics and prebiotics function at distant sites?
Reid, G., Abrahamsson, T., Bailey, M., Bindels, L.B., Bubnov, R., Ganguli, K., Martoni, C., O’Neill, C., Savignac, H.M., Stanton, C., Ship, N., Surette, M., Tuohy, K., van Hemert, S.
Beneficial Microbes, 2017. 8(4).

The microbiota-gut-brain axis as a key regulator of neural function and the stress response: Implications for human and animal health.
Wiley, N.C., Dinan, T.G., Ross, R.P., Stanton, C., Clarke, G., Cryan, J.F.
Journal of Animal Science, 2017. 95(7). DOI: 10.2527/jas.2016.1256

Fat binding capacity and modulation of the gut microbiota both determine the effect of wheat bran fractions on adiposity.
Suriano, F., Bindels, L.B., Verspreet, J., Courtin, C.M., Verbeke, K., Cani, P.D., Neyrinck, A.M., Delzenne, N.M.
Scientific Reports, 2017. 7(1). DOI: 10.1038/s41598-017-05698-y

Will gut microbiota help design the next generation of GLP-1-based therapies for type 2 diabetes?
Claus, S.P.
Cell Metabolism, 2017. Vol. 26.

Feeding the microbiota: transducer of nutrient signals for the host.
Shanahan, F., van Sinderen, D., O’Toole, P.W., Stanton, C.
Gut, 2017. 66(9). DOI: 10.1136/gutjnl-2017-313872

Microbiota-Gut-Brain Axis: Modulator of Host Metabolism and Appetite.
van de Wouw, M., Schellekens, H., Dinan, T.G., Cryan, J.F.
Journal of Nutrition, 2017. 147(5). DOI: 10.3945/jn.116.240481

Intervention strategies for cesarean section–induced alterations in the microbiota-gut-brain axis.
Moya, A., Luczynski, P., Renes, I.B., Wang, S., Borre, Y., C. Ryan, C., Knol, J., Stanton, J., Dinan, T.G., and Cryan, J.F.
Nutrition Reviews, 2017. 75(4). DOI: 10.1093/nutrit/nuw06

Complete genome sequence of the gamma-aminobutyric acid-producing strain Streptococcus thermophilus APC151.
Linares, D.M., Arboleya, S., Ross, R.P., and Stanton, C.
Genome announcements, 2017. Vol. 5. DOI: 10.1128/genomeA.00205-17

A psychology of the human brain-gut-microbiome axis.
Allen, A.P., Dinan, T.G., Clarke, G., Cryan, J.F.
Social and Personal Psychology Compass, 2017. 11(4).

The Microbiome-Gut-Brain Axis in Health and Disease.
Dinan, T.G., Cryan, J.F.
Gastroenterology Clinics of North America, 2017. Vol. 46. DOI: 10.1016/j.gtc.2016.09.007

Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice.
Burokas, A., Arboleya, S., Moloney, R.D., Peterson, V.L., Murphy, K., Clarke, G., Stanton, C., Dinan, T.G., Cryan, J.F.
Biological Psychiatry, 2017. 82(7). DOI: 10.1016/j.biopsych.2016.12.031

Gut-brain axis in 2016: Brain-gut-microbiota axis - mood, metabolism and behaviour.
Dinan, T.G., Cryan, J.F.
Nature Reviews Gastroenterology & Hepatology, 2017. 14(2). DOI: 10.1038/nrgastro.2016.200

Feeding the microbiota-gut-brain axis: diet, microbiome, and neuropsychiatry.
Sandhu, K.V., Sherwin, E., Schellekens, H., Stanton, C., Dinan, T.G., and Cryan, J.F.
Translational Research, 2017. Vol. 179.

Microbes, Immunity, and Behavior: Psychoneuroimmunology Meets the Microbiome.
Dinan, G.T., Cryan, J.F.
Neuropsychopharmacology, 2017. 42(1). DOI: 10.1038/npp.2016.103

Omega-3 polyunsaturated fatty acids critically regulate behaviour and gut microbiota development in adolescence and adulthood.
Robertson, R.C., Oriach, C.S., Murphy, K., Moloney, G.M., Cryan, J.F., Dinan, T.G., Ross, R.P., and Stanton, C.
Brain, Behavior, and Immunity, 2017. Vol. 59.

The composition of human milk and infant faecal microbiota over the first three months of life: a pilot study.
Murphy, K., Curley, D., O’Callaghan, T.F., O’Shea, C.-A., Dempsey, E.M., O’Toole, P.W., Ross, R.P., Ryan, C.A., and Stanton, C.
Scientific Reports, 2017. Vol. 7. DOI: 10.1038/srep40597

Probiotic, Prebiotic and Brain Development.
Cerdó, T., Ruíz, A., Suárez, A., Campoy, C.
Nutrients, 2017. Vol. 9. DOI: 10.3390/nu9111247.

The Brain-Gut Axis Contributes to Neuroprogression in Stress-Related Disorders.
Rea, K., Dinan, T.G., Cryan, J.F.
Modern Trends in Pharmacopsychiatry, 2017. Vol. 31. DOI: 10.1159/000470813

Human Gut Microbiota and Obesity During Development.
Cerdó, T., Ruiz, A., and Campoy, C.
In tech, 2017. DOI: 10.5772/65928

Epithelial response to a high-protein diet in rat colon.
Beaumont, M., Andriamihaja, M., Armand, L., Grauso, M., Jaffrézic, F., Laloë, D., Moroldo, M., Davila, A.M., Tomé, D., Blachier, F., Lan, A.
BMC Genomics, 2017. 18(1). DOI: 10.1186/s12864-017-3514-z.




MyNewGut Special Issue: Unravelling the role of the gut microbiome in energy balance and brain development and function: the European project MyNewGut

Brigidi P, Sanz Y.
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.11.002.


Impact of dietary fiber and fat on gut microbiota re-modeling and metabolic health.
Benítez-Páez A, Gómez Del Pulgar EM, Kjølbæk L, Kirchner Brahe L, Astrup A, Hingstrup Larsen L, Sanz Y.
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.11.001.


Gut microbiota role in dietary protein metabolism and health-related outcomes: The two sides of the coin.
Portune K.J, Beaumont M, Davila A, Tomé D, Blachier F, Sanz Y.
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.08.011.


Interplay between gut microbiota, its metabolites and human metabolism: Dissecting cause from consequence.
Hartstra A.V, Nieuwdorp M, Herrema H. 
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.08.009.


Metabolomics of fecal samples: A practical consideration.
Matysik S, Le Roy C, Gerhard L, Claus S.
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.05.011.

Microbiome and metabolic disorders related to obesity: Which lessons to learn from experimental models?
Neyrinck AM, Schüppel VL, Lockett T, Haller D, Delzenne NM. 

Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.08.012.


Microbiota and lifestyle interactions through the lifespan.
Rampelli S, Candela M, Turroni S, Biagi E, Pflueger M, Wolters M, Ahrens W, Brigidi P.
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.03.003.


Role of microbiota during early life on child's neurodevelopment.
Cerdóa T, García-Valdésa L, Altmäeb S, Ruízd A, Suárezd A, Campoy C. 
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.08.007.


Microbiome in brain function and mental health.
Kennedy PJ, Murphy A.B, Cryan JF, Ross PR, Dinan TG. 
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.05.001.


The human gut microbiome, diet, and health: “Post hoc non ergo propter hoc”.
Roeselers G, Bouwman J, Levin E.
Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.08.010.


Insulin resistance as key factor for linking modulation of gut microbiome to health claims and dietary recommendations to tackle obesity.          

Loman S, Van der Kamp JW.

Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.10.008.


Communication and impact through targeted channels and media.

Giordani A, Sadler C,Fernández L.

Trends Food Sci Technol. 2016 Nov; 57(part B). doi: 10.1016/j.tifs.2016.10.007.


The role of microbiota and Intestinal permeability in the pathophysiology of autoimmune and neuroimmune processes with an emphasis on Inflammatory Bowel Disease, Type 1, Diabetes and Chronic Fatigue Syndrome. Morris G, Berk M, Carvalho AF, Caso JR, Sanz Y, Maes M.

Curr Pharm Des. 2016 Sep 14. [Epub ahead of print]


Intestinal dysbiosis, gut hyperpermeability and bacterial translocation: missing links between depression, obesity and type 2 diabetes?  Slyepchenko A, Maes M, Machado-Veira R, Anderson G, Solmi M, Sanz Y, Berk M, Köhler CA, Carvalho AF.

Curr Pharm Des. 2016 Sep 22. [Epub ahead of print]


The Role of the Microbial Metabolites Including Tryptophan Catabolites and Short Chain Fatty Acids in the Pathophysiology of Immune-Inflammatory and Neuroimmune Disease.
Morris G, Berk M, Carvalho A, Caso JR, Sanz Y, Walder K, Maes M.
Molecular Neurobiology. 2016 Jun 27. doi: 10.1007/s12035-016-0004-2.
PMID: 27349436.


The gut microbiota: a major player in the toxicity of environmental pollutants? 

Claus S, Guillou H, Ellero-Simatos S.

Biofilms and Microbiomes. 2016 May 4. doi: 10.1038/npjbiofilms.2016.3


Genome structure of the symbiont Bifidobacterium pseudocatenulatum CECT 7765 and gene expression profiling in response to lactulose-derived oligosaccharides.
Benítez-Páez A, Moreno FJ, Sanz ML, Sanz Y. 
Front Microbiol. 2016 Apr 29;7:624. doi: 10.3389/fmicb.2016.00624.
PMID: 27199952.


ViromeScan: a new tool for metagenomic viral community profiling.
Rampelli S, Soverini M, Turroni S, Quercia S, Biagi E, Brigidi P, Candela M.
BMC Genomics. 2016 March 1. doi: 10.1186/s12864-016-2446-3.
PMID: 26932765


Detrimental effects for colonocytes of an increased exposure to luminal hydrogen sulfide: The adaptive response.

Beaumont M, Andriamihaja M, Lan A, Khodorova N, Audebert M, Blouin JM, Grauso M, Lancha L, Benetti PH, Benamouzig R, Tome D, Bouillaud F, Davila AM, Blachier F.
Free Radic Biol Med. 2016 April. doi: 10.1016/j.freeradbiomed.2016.01.028.
PMID: 26849947

Species-level resolution of 16S rRNA gene amplicons sequenced through the MinION™ portable nanopore sequencer.

Benítez-Páez A, Portune KJ, Sanz Y. 
Gigascience. 2016 Jan 28;5:4. doi: 10.1186/s13742-016-0111-z.
PMID: 26823973.

Safety Assessment of Bacteroides uniformis CECT 7771 Isolated from Stools of Healthy Breast-Fed Infants.

Fernández-Murga ML, Sanz Y.
PLoS One. 2016 Jan 19;11(1):e0145503. doi: 10.1371/journal.pone.0145503. 
PMID: 26784747

Bifidobacterium pseudocatenulatum CECT7765 induces an M2 anti-inflammatory transition in macrophages from patients with cirrhosis.

Moratalla A, Caparrós E, Juanola O, Portune K, Puig-Kröger A, Estrada L,Bellot P, Gómez-Hurtado I, Piñero P, Zapater P, González-Navajas JM, Such J, Sanz Y, Francés R.
Journal of Hepatology. 2016 Jan. doi: 10.1016/j.jhep.2015.08.020.
PMID: 26334579.  


Adult microbiota-deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus.

Luczynski, P., Whelan, S.O., O'Sullivan, C., Clarke, G., Shanahan, F., Dinan, T.G., Cryan, J.F.
European Journal of Neuroscience, 2016. Vol. 44.

Psychobiotics and the Manipulation of Bacteria-Gut-Brain Signals.
Sarkar, A., Lehto, S.M., Harty, S., Dinan, T.G., Cryan, J.F., Burnet, P.W.
Trends in Neuroscience, 2016. 39(11). DOI: 10.1016/j.tins.2016.09.002

May the Force Be With You: The Light and Dark Sides of the Microbiota-Gut-Brain Axis in Neuropsychiatry.
Sherwin, E., Sandhu, K.V., Dinan, T.G., Cryan, J.F.
CNS Drugs, 2016. Vol. 30. DOI: 10.1007/s40263-016-0370-3

What's bugging your teen? - The microbiota and adolescent mental health.
McVey Neufeld, K.A., Luczynski, P., Seira Oriach, C., Dinan, T.G., Cryan, J.F.
Neuroscience & Biobehavioral Reviews, 2016. Vol. 70. DOI: 10.1016/j.neubiorev.2016.06.005

Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat.
Kelly, J.R., Borre, Y., O' Brien, C., Patterson, E., El Aidy, S., Deane, J., Kennedy, P.J., Beers, S., Scott, K., Moloney, G., Hoban, A.E., Scott, L., Fitzgerald, P., Ross, P., Stanton, C., Clarke, G., Cryan, J.F., Dinan, T.G.
Journal of Psychiatric Research, 2016. Vol. 82. DOI: 10.1016/j.jpsychires.2016.07.019

The neuropharmacology of butyrate: The bread and butter of the microbiota-gut-brain axis?
Stilling, R.M., van de Wouw, M., Clarke, G., Stanton, C., Dinan, T.G., Cryan, J.F.
Neurochemistry International, 2016. Vol. 99. DOI: 10.1016/j.neuint.2016.06.011

From bacterial genomics to human health.
Sanz, Y., Benítez-Páez, A.
Fermented Foods in Health and Disease Prevention, 2017.

Microbe-host interactions: Influence of the gut microbiota on the enteric nervous system.
Hyland, N.P., Cryan, J.F.
Developmental Biology, 2016. Vol. 417.

Growing up in a Bubble: Using Germ-Free Animals to Assess the Influence of the Gut Microbiota on Brain and Behavior.
Luczynski, P., McVey Neufeld, K.A., Oriach, C.S., Clarke, G., Dinan, T.G., Cryan, J.F.
International Journal of Neuropsychopharmacology, 2016. Vol. 19. DOI:

Targeting the microbiota: considerations for developing probiotics as functional foods.
Sanz, Y., Portune, K., Gómez del Pulgar, E.M., Benítez-Páez, A.
Targeting the Microbiota: Considerations for Developing Probiotics as Functional Foods, 2016. Pages 17-30.

Species-level resolution of 16S rRNA gene amplicons sequenced through the MinION™ portable nanopore sequencer.
Benítez-Páez, A., Portune, K.J., Sanz, Y.
GigaScience, 2016. Vol. 5.




Birth by Caesarean Section and the Risk of Adult Psychosis: A Population Based Cohort Study.
O'Neill SM, Curran EA, Dalman C, Kenny LC, Kearney PM, Clarke G, Cryan JF, Dinan TG, Khashan AS.
Schizophr Bull. 2015 Nov; 45 (3): 633-641. doi: 10.1093/schbul/sbv152.
PMID: 26615187.

Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders.
Kelly JR, Kennedy PJ, Cryan JF, Dinan TG, Clarke G, Hyland NP. 
Front Cell Neurosci. 2015 Oct; 9: 392. doi: 10.3389/fncell.2015.00392.
PMID: 26528128.  


Adult Hippocampal Neurogenesis Is Regulated by the Microbiome.

Ogbonnaya ES, Clarke G, Shanahan F, Dinan TG, Cryan JF, O'Leary OF.
Biological Psychiatry. 2015 Aug; 78(4). doi: 10.1016/j.biopsych.2014.12.023.
PMID: 25700599.

When ageing meets the blues: Are current antidepressants effective in depressed aged patients?
Felice D, O'Leary OF, Cryan JF, Dinan TG, Gardier AM, Sanchez C, David DJ.
Neuroscience and Behavioural Reviews. Aug 2015; 55:478-497. doi: 10.1016/j.neubiorev.2015.06.005.

PMID: 26054791.


Foodomics for personalized nutrition: how far are we?

Vimaleswaran KS, Le Roy CI, Claus SP.
Current Opinion in Food Science. 2015 Aug; 4:129-135. doi: 10.1016/j.cofs.2015.07.001.

The deleterious metabolic and genotoxic effects of the bacterial metabolite p-cresol on colonic epithelial cells.

Andriamihaja M, Lan A, Beaumont M, Audebert M, Wong X, Yamada K, Yin Y, Tomé D, Carrasco-Pozo C, Gotteland M, Kong X, Blachier F.
Free Radic Biol Med. 2015 Aug; 85:219-27. doi: 10.1016/j.freeradbiomed.2015.04.004. 
PMID: 25881551


Gut microorganisms as promising targets for the management of type 2 diabetes.

Delzenne NM, Cani PD, Everhard A, Neyrinck AM, Bindels LB.
Diabetologia. 2015 July; 58 (10): 2206-2217.
PMID: 26224102


Microbiota and host determinants of behavioural phenotype in maternally separated mice.

De Palma G, Blennerhassett P, Lu J, Deng Y, Park AJ, Green W, Denou E, Silva MA, Santacruz A, Sanz Y, Surette MG, Verdu EF, Collins SM, Bercik P.
Nature Communications. 2015 July 28; 6: 7735. doi: 10.1038/ncomms8735.
PMID: 26218677

Understanding the role of gut microbiome in metabolic disease risk.
Sanz Y, Olivares M, Moya-Pérez Á, Agostoni C.
Pediatr Res. 2015 Jan; 77(1-2):236-44. doi: 10.1038/pr.2014.170. Epub 2014 Oct 14.
PMID: 25314581.


Insights into the role of the microbiome in obesity and type 2 diabetes.

Hartstra AV, Bouter KE, Bäckhed F, Nieuwdorp M.
Diabetes Care. 2015 Jan; 38(1):159-65. doi: 10.2337/dc14-0769.
PMID: 25538312.


Diet-induced obesity causes metabolic impairment independent of alterations in gut barrier integrity.
Kless, C., Müller, V.M., Schüppel, V.L., Lichtenegger, M., Rychlik, M., Daniel, H., Klingenspor, M., Haller, D.
Molecular Nutrition & Food Research, 2015. Vol. 59.




Mammalian-microbial cometabolism of L-carnitine in the context of atherosclerosis.
Claus SP.
Cell Metab. 2014 Nov 4; 20(5):699-700. doi: 10.1016/j.cmet.2014.10.014. 
Epub 2014 Nov 4.
PMID: 25440049.


Development of personalized functional foods needs metabolic profiling.
Claus SP.
Curr Opin Clin Nutr Metab Care. 2014 Nov; 17(6):567-73. doi: 10.1097/MCO.0000000000000107.
PMID: 25137506.


High protein diet modifies colonic microbiota and luminal environment but not colonocyte metabolism in the rat model: The increased luminal bulk connection.
Liu X, Blouin JM, Santacruz A, Lan A, Andriamihaja M, Wilkanowicz S, Benetti PH, Tome D, Sanz Y, Blachier F, Davilla AM. 
American Journal of Physiology. 2014 June 26. doi: 10.1152/ajpgi.00400.2013
PMID: 24970777.




The human gastrointestinal microbiota - an unexplored frontier for pharmaceutical discovery.
Roeselers, G., Bouwman, J., Venema, K., Montijn, R.
Pharmacological Research, 2012. Vol. 66.