News

MyNewGut Final Conference: highlights and project's achievements

 

On Thursday 18th October 2018, EUFIC hosted MyNewGut final conference at the Stanhope Hotel in Brussels. The conference marked the culmination of the project, which over the last five years, looked at the gut microbiome to prevent diet-related and behavioural disorders. The event was attended by around 120 participants, including representatives from the European Commission, project partners and interested stakeholders.

 The main aim of the conference was to bring all consortium partners together and present the ground-breaking results of five years of research. The results have shown that the influence of the gut microbiota on health is complex. Many factors such as proteins, fats and fibre all have different impacts on the microbiome and metabolites depending on the food source and quantity. Besides, influence on gut health they also affect cognitive function and incidence of depression. The outcomes are expected to support new dietary recommendations to guide consumers towards healthier food choices such as high intake of all fibres, choosing polyunsaturated fats (seeds, nuts fish) over saturated fat and being cautious in utilising high-protein diets on the long-term for weight loss.

 The event was inaugurated with a keynote speech by Barend Verachtert, Head of Agri-Food Chain Unit of DG Research & Innovation, EC with made a powerful statement “Scientific research is useless without empowerment of the community” in his talk about Food2030. Next, Dirk Hadrich, Innovative and Personalised Medicine Unit, Health Directorate, DG Research & Innovation, EC, went into more depth about funding human microbiome research in the European Union (EU). The first session concluded with project coordinator, Yolanda Sanz, giving an overview of the main project achievements.

 The second session focused on ‘Microbiome-diet interactions in obesity and eating behaviour’, with Francois Blachier from INRA, France, talking about High-Protein Diets (HPD). Followed by Max Nieuwdorp from AMC, The Netherlands discussing what matters in metabolic health – microbes, metabolites or both. Next, Patrizia Brigidi from UNIBO, Italy compared obese and lean gut microbiota. And Sandrine Claus form UREAD, UK closed the session with a talk about on personal metabolic responses to diet.

 In the third session ‘Gut-brain axis: A new route for programming health and mood’, four keynote speakers took the lead. First, Catherine Stanton from UCC, Ireland talked about the impact of microbiota on the immune system of children. After, Cristina Campoy from UGR, Spain spoke about factors influencing the gut microbiome in the PREOBE study. Next, Peter Holzer from MUG, Austria talked about the impact of a high fat diet on the gut and on mental health. And Ted Dinan from UCC, Ireland concluded the session with a talk on psychobiotics and stress resilience.

 The focus of the fourth session was on ‘Translating microbiome science into applications.’ The two keynote speakers were Nathalie Delzenne from UCL, Belgium explaining the dietary fibre impact on gut microbiota and the role of DDP-4 on the gut-liver axis. Thomas Meinert Larsen from UCPH, Denmark explained a send-for-publication study on prebiotic supplementation.  

Two keynote speakers covered the fifth session of the day ‘Implications of microbiome science for public health’. Namely, Jan-Willem van der Kamp from TNO, The Netherlands with a talk on microbiome-informed dietary guidelines on protein, fats and dietary fibre intake recommendations. And a second talk of the day for Ted Dinan on the role of microbiota In Major Depression, together with treating recommendations.

 The closing session was chaired by project coordinator Yolanda Sanz speaking words of thanks to all attendees and partners of the consortium. The finishing talk was held by Carina Pereira from DG Research & Innovation, EC highlighting the next steps towards a climate-smart and sustainable food system for a healthy Europe.

You can find the speakers presentations below:

  • Barend Verachtert - 'Food 2030: Research and innovation for food and nutrition security'. Download here
  • Dirk Hadrich - 'Funding human microbiome research in the EU'. Download here
  • Yolanda Sanz - 'MyNewGut: Overview of the main project achievements'. Download here
  • Francois Blachier - 'Dietary proteins: Goodness and warning for weight management'. Download here
  • Max Nieuwdorp - 'What matters to metabolic health: Microbes, metabolites or both?'. Download here
  • Patrizia Brigidi - 'Gut microbiome as predictors of obesity and addictive-eating behaviour'. Download here
  • Catherine Stanton - 'Impact of early life factors on the devloping gut microbiota and the stress response'. Download here
  • Cristina Campoy - 'Diet, microbiota and neurodevelopment'. Download here
  • Peter Holzer - 'Diet, microbiota and emotional behaviour'. Download here
  • Nathalie Delzenne, UCL, Belgium - 'Understanding specificities of fibre-microbiome interactions: how can this help?'. Download here
  • Ted Dinan - 'Developing a psychobiotic for stress'. Download here
  • Ted Dinan - 'Feeding melancholic microbes'. Download here
  • Carina Pereira - 'Next steps towards a climate-smart and sustainable food system for a healthy Europe'. Download here

 

The MyNewGut project leaflet describes the project's objectives, and summarises the following research findings:

 

  • Bacterial strains in our gut could be the next generation of probiotics
  • Consuming an excess of proteins generates some of the toxic metabolites
  • Diets rich in fibres are associated with fewer symptoms of depression, help to maintain body weight, reduce the risk of developing chronic metabolic diseases
  • A high fat diet may have a negative impact on the gut microbiota and the brian
  • The gut microbiota influences metabolic health

Download the leaflet here.

Gut – Brain – Microbiome Symposium in Alsace, France on 10-13 October 2018

Gut – Brain – Microbiome Symposium poster
 
One of the MyNewGut project partners, Nathalie Delzenne, organised a Symposium in Alsace, France on 10-13 October 2018. During this symposium, the brain – gut - microbiome network in metabolic regulation and dysregulation was discussed.
Several MyNewGut partners presented during this 3-day meeting. 
  • Peter Holzer from the University of Graz, Austria, talked about gut – brain – microbiome interactions in obesity and depression.
  • Patrizia Brigidi from the University of Bologna, Italy, presented her finding on the gut microbiota of centenarians and how that relates to signatures of longevity in the gut microbiota profiles.
  • Nathalie Delzenne, from the University of Louvain, Belgium, gave her presentation about feeding the gut microbiota with prebiotic dietary fibers and how that relates to the therapeutic interest in metabolic disorders.
 
Download the Symposium poster here.

The Human Microbiome Symposium at EMBL in Heidelberg

The Human Microbiome Symposium was held at EMBL in Heidelberg. 

 

 The following MyNewGut partner presentations were given during the event:

  • Social microbes: microbiome as a key regulator of brain and behaviour 
      John F Cryan University College Cork, Ireland
 
  • Tackling metabolic health through diet-microbiome-host alliances 
      Yolanda Sanz National Research Council, Spain
 
  • Using FMT to dissect causality in human cardiometabolic disease: from lead to cure 
      Max Nieuwdorp Academic University Medical Center, The Netherlands
 
Download the programme here.

Technical Workshop on Food Safety and Healthy Diets, at Vatican City, 12-13 September

The key objective of the Summit is to explore how to tackle all forms of malnutrition by increasing the availability and affordability of safe and nutritious foods for all on a sustainable basis.

The key objective of the Summit is to explore how to tackle all forms of malnutrition by increasing the availability and affordability of safe and nutritious foods for all on a sustainable basis. The MyNewGut project coordinator Dr Yolanda Sanz of the Spanish National Research Council (CSIC) particpated in the workshop.

Download the programme booklet here.

MyNewGut partners to speak at the 43rd Symposium on Hormomes and Cell Regulation

 

 

MyNewGut partners Nathalie Delzenne (UCL), Peter Holzer (University of Graz), Patrizia Brigidi (University of Bologna) and Max Nieuwdorp (University of Amsterdam) will take part in the next Symposium on Hormones and Cell Regulation organized by the European Society of Edocrinology.

 
What is the conference about?

 

This symposium will deal with the interactions between the brain, the gut and the microbiome as a crucial network involved in metabolic regulation, obesity, type 2 diabetes and neurodegenerative disorders. The main topics to be covered will be:

  1. Cross-talk between the brain and the gut in metabolic regulation.
  1. The gut microbiota: a complex ecosystem and its interaction with host cells.
  1. New mediators/targets in gut function.
  1. The gut microbiome in metabolic regulation and dysregulation across lifespan.
  1. The gut microbiome and CNS dysfunction
  1. Therapeutic perspectives

 

Consult with the Programme here.

Register here.

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